With CRISPR, a possible quick test for the COVID19 | via nytimes
A team of scientists has developed an experimental prototype for a fairly quick, cheap test to diagnose the coronavirus that gives results as simply as a pregnancy test does.
Two other teams of researchers, one in Buenos Aires, Argentina, and the other in San Francisco, are also working to devise new tests to detect the virus using gene-editing technology. Mullis won the Nobel Prize in 1993 for inventing PCR. It proved to be a workhorse for biological research, as well as for forensic DNA tests and other applications. In January, when scientists discovered the coronavirus that causes COVID-19, they used its genetic sequence to create PCR tests for it.
“You really need new technologies that are more distributed, that don’t require thousands of trained people or need centralized labs,” said Omar Abudayyeh of MIT, one of Zhang’s collaborators. In recent years, scientists have figured out new things to do with CRISPR’s tags and enzymes. Zhang and other researchers have been retooling it as a way to detect viruses.
Earlier this year, they adapted the Sherlock test to find the coronavirus. But their test, like those from other groups, required moving a sample into a series of tubes to carry out separate reactions.
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