US approves Alzheimer’s drug that slows disease
The American Food and Drug Administration has approved a closely watched Alzheimer’s drug that modestly slows the brain-robbing disease, albeit with potential safety risks that patients and their doctors will have to weigh carefully.
Snider stressed that the medicine, pronounced “leh-KEM-bee”, comes with downsides, including the need for twice-a-month infusions and possible side effects like brain swelling. Some 6 million people in the US and many more worldwide have Alzheimer’s, which gradually attacks areas of the brain needed for memory, reasoning, communication and daily tasks.
There is little consensus on whether that difference translates into real benefits for patients, such as greater independence. “Is this slight, measurable benefit worth the hefty price tag and the side effects patients may experience?” he asked. “I have pretty serious doubts.” A key question in the drug’s rollout will be the coverage decision by Medicare, the US federal health plan that covers 60 million seniors and other Americans. The agency severely restricted coverage of Aduhelm, essentially wiping out its US market and prompting Biogen to abandon marketing plans for the drug.
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