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A group of scientists from the University of the Philippines Diliman discovered a key protein that contributes to the progression of prostate cancer into its most aggressive form, neuroendocrine prostate cancer .Scientists from the UP Diliman College of Science National Institute of Molecular Biology and Biotechnology discovered that a protein called CYB561 contributes to the progression, growth, and survival of aggressive, treatment-resistant prostate cancer cells.
According to the World Health Organization, in 2022, prostate cancer was the third most common type of cancer among Filipino men, with 9,764 cases diagnosed that year.If it progresses into an NEPC, it is resistant to ADT as a treatment.Further, the scientists also found that “CYB561 converts iron into a more active form essential for various cell processes, including supporting the growth of aggressive forms of cancer.
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