Pfizer-BioNTech on Tuesday filed an application with US regulators seeking emergency use authorization for a second booster shot of their COVID-19 vaccine for people aged 65 and older.
The submission to the US Food and Drug Administration includes data collected in Israel, where a second booster is authorized for many people over age 18.
Pfizer Chief Executive Albert Bourla has several times in the past week told reporters that a fourth dose of the vaccine will be needed to offset waning protection gained with the third shot. "The elderly and immunocompromised are the groups that would benefit the most from additional boost," said Dan Barouch, a Harvard vaccine researcher. "I think the data is supportive, but the benefits appear to be relatively small."
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