Australian doctors are testing out a ‘snot transplant’ to treat chronic nose problems - hoping to repeat in the upper airways the breakthrough success of poo transplants.
infection with a faecal transplant, which transfers poo — and the healthy bacteria it contains — from one donor to another.Cervin hopes to now repeat the trick in the nose for patients with sinusitis. Also known as chronic rhinitis, it is inflammation of the sinuses that has lasted longer than three months. It is also incredibly widespread,Jean Bryant has lived with sinusitis for 12 years. It has left her with no sense of smell or taste.“I can’t smell fire or petrol or gas,” she says.
There is some evidence this is the case, says University of Technology Sydney Professor Hui Chen, who studies the role of the nasal microbiome in disease. But it’s not clear if it is cause or effect — if an unhealthy noseTo test his theory, 60 volunteers will get two weeks of antibiotics to try to kill off anything living in their noses.
Then the donor has water gently washed up into their nose for a few minutes. The ‘nasal wash’, full of mucus, snot and hopefully healthy bacteria, is then sprayed into the patient’s nose. The spray will be done every day for a week to give the bacteria the best chance of sticking. Will it work? A pilot trial run by Cervin in Sweden reported promising results, with evidence the treatment significantly increased the diversity of the nasal microbiome — and patients reported an improvement in their symptoms.“It is an exciting idea,” said Professor Peter John Wormald, chair of head and neck surgery at the University of Adelaide. However, a healthy nose’s microbiome is very small, he said; there’s really not much to transfer.
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