Moore stars as Elisabeth, an aging TV fitness instructor a la Jane Fonda who signs up for a mysterious medical regime called The Substance that promises to create the perfect version of herself
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– played by Margaret Qualley ofThe role requires Moore, 61, to be completely naked as well as transform into a deteriorating old woman through prosthetics. “The level of vulnerability that this role called for on all the different levels – emotionally, physically – were as demanding as it was exciting because it was really pushing me to step out of my comfort zone,” said Moore.
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