WASHINGTON: Evidence is growing about the many ways that traveling in the microgravity environment of space tampers with the human body, with new research showing how it dials down the activity of genes in white blood cells crucial to the immune system. A study involving 14 astronauts who spent four and a
WASHINGTON: Evidence is growing about the many ways that traveling in the microgravity environment of space tampers with the human body, with new research showing how it dials down the activity of genes in white blood cells crucial to the immune system.
"A weaker immunity increases the risk of infectious diseases limiting astronauts' ability to perform their very demanding work in space. If an infection or an immune-related condition was to evolve to a severe state requiring medical care, astronauts while in space would have limited access to care and medication," said molecular biologist Odette Laneuville of the University of Ottawa in Canada, lead author of the research published in the journal Frontiers in Immunology.
"White blood cells are very sensitive to the environment of space. They trade their specialized immune functions to take care of cell maintenance or housekeeping roles. Before this paper, we knew of immune dysfunction but not of the mechanisms," said study co-author Guy Trudel, an Ottawa Hospital rehabilitation medicine specialist.
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