A third booster dose of a COVID-19 vaccine made by AstraZeneca, Pfizer-BioNTech or Johnson & Johnson increases antibody levels significantly in those who have previously received two doses of Sinovac’s CoronaVac shot, a study has found.
The study found that CoronaVac received the strongest boost from a viral vector or RNA shot, including against the Delta and Omicron coronavirus variants, researchers fromChina-based Sinovac’s vaccine uses an inactivated version of a coronavirus strain that was isolated from a patient in China. It is currently approved in more than 50 countries including Brazil, China, Argentina, South Africa, Oman, Malaysia, Indonesia and Turkey.
However, another study in December found that Sinovac’s two-dose shot followed by a booster dose of Pfizer-BioNTech’s vaccine showed a lower immune response against the Omicron variant compared with other strains. Pfizer and BioNTech’s mRNA vaccines deliver a genetic transcript with instructions for making viral proteins to teach the body how to defend against infections.
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