As the largest variant of the histone H2A family, macroH2A plays significant regulatory roles in various processes such as X-chromosome inactivation, embryonic development, cellular metabolism, and tumorigenesis due to its unique linker and macro domains.
Scientists discover molecular mechanism that plays key role in gene transcription and macrophage functional activation retrieved 30 August 2024 from https://phys.org/news/2024-08-scientists-molecular-mechanism-plays-key.html
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