New study finds most medications are ineffective against strains currently circulating but thankfully full vaccination still offers protection
Monoclonal antibody treatments are laboratory-made proteins designed to mimic the natural antibodies produced by the immune system, stopping the virus from replicating. The drugs, which include Sotrovimab and Evusheld, are delivered intravenously.examined the ability of approved monoclonal antibody therapies to neutralise currently circulating variants – and the treatments fared poorly.
The paper concluded that “treatment in the era of a variant mix will provide many challenges and will require continued monitoring”. Paxlovid – an oral antiviral medication that works by hampering a key enzyme the virus needs to replicate – remains effective against the variants, the paper found. It has been known since the emergence of Omicron variants BA.1 and BA.2 that two-dose vaccination is not enough for good protection and Turville said this was clearer still with the current BR.2.1 and XBF variants.
Overall Covid case numbers reduced throughout December but there are a concerning number of deaths occurring despite access to booster doses and Paxlovid. In the week to 30 December, Victoria recorded 69 deaths, NSW 32 and South Australia 18.
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