.CNN OPINION: A new approach to managing the COVID-19 pandemic now could be on the table: antiviral pills
said their results demonstrate their novel drug molnupiravir cut in half the rate of hospitalization and death in persons with mild to moderate disease. If authorized by the US Food and Drug Administration for emergency use, the pill would become the first oral medicine to fight viral infection for COVID-19.
If the results hold up to scientific scrutiny, this is very big news indeed. Effective pills given to outpatients could make a large difference for several distinct groups: for people with mild illness, it could prevent progression to more severe, even life-threatening illness, as the study apparently shows; provide an alternative approach to prevent severe disease in vaccine-refuseniks and vaccine-non-responders ; and potentially protect those with recent close exposure to an active case .
We have limited study information so far, so caution is advised. However, the most promising"tell" is the decision of the Data Safety and Monitoring Board , a group of outside experts not involved in the trial, whoregularly with no idea which people are receiving the drug and which are receiving placebo. They just look at extracted raw numbers.
Thankfully, the group with the better outcome turned out to be those on molnupiravir, not placebo. Of those 775 participants, all had at least one co-morbid condition placing them at higher risk for progression to severe disease; 385 received the active drug and saw their rate of hospitalization or death reduce from the 14.1% seen in the placebo group to 7.3%,All good for sure.
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