Novo Nordisk says obesity pill leads to 15% weight loss; availability 'to be determined'

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Novo Nordisk says obesity pill leads to 15% weight loss; availability 'to be determined'
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SAN DIEGO: Novo Nordisk on Sunday (Jun 25) said a late-stage trial found that a high-dose oral version of its drug semaglutide helped overweight or obese adults lose 15 per cent of their body weight, which is in line with recent results for other experimental obesity pills. Novo plans to seek US and Europe

SAN DIEGO: Novo Nordisk on Sunday said a late-stage trial found that a high-dose oral version of its drug semaglutide helped overweight or obese adults lose 15 per cent of their body weight, which is in line with recent results for other experimental obesity pills.

The drug, designed to activate hormones that regulate blood sugar, slow stomach emptying and decrease appetite, is part of a new class that has reignited researcher and investor interest in the"We are upping production as much as we can," Guevarra said in an interview here on the sidelines of the annual meeting of the American Diabetes Association.

These results are in line with preliminary data from the late-stage trial released by the company in May.Oral semaglutide, according to the FDA label, needs to be taken in the morning on an empty stomach, 30 minutes before eating, drinking, or using any other oral medication - you are allowed only 4 ounces of plain water. If you eat too soon, the pill is less effective, but if you wait longer than 30 minutes its absorption may be enhanced.

At the ADA meeting on Friday, results from an Eli Lilly mid-stage trial showed that the highest dose of its experimental pill orforglipron helped people who were obese or overweight lose 14.7 per cent of their body weight after 36 weeks, and their weight loss had not yet appeared to plateau.

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