Nobel win for Swede who unlocked secrets of Neanderthal DNA

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Nobel win for Swede who unlocked secrets of Neanderthal DNA
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Swedish scientist Svante Paabo won the Nobel Prize in medicine Monday for his discoveries on human evolution.

Paabo spearheaded the development of new techniques that allowed researchers to compare the genome of modern humans and that of other hominins — the Neanderthals and Denisovans.Sign up to receive daily headline news from the Calgary SUN, a division of Postmedia Network Inc.By clicking on the sign up button you consent to receive the above newsletter from Postmedia Network Inc. You may unsubscribe any time by clicking on the unsubscribe link at the bottom of our emails. Postmedia Network Inc.

Wedell described this as “a sensational discovery” that subsequently showed Neanderthals and Denisovan to be sister groups which split from each other around 600,000 years ago. Denisovan genes have been found in up to 6% of modern humans in Asia and Southeast Asia, indicating that interbreeding occurred there too.

He mused about what would have happened if Neanderthals had survived another 40,000 years. “Would we see even worse racism against Neanderthals, because they were really in some sense different from us? Or would we actually see our place in the living world quite in a different way when we would have other forms of humans there that are very like us but still different,” he said.

When you sequence DNA from a fossil millions of years old, you only have “vanishingly small amounts” of DNA, Green said. Among Paabo’s innovations was figuring out the laboratory methods for extracting and preserving these tiny amounts of DNA. He was then able to lay pieces of the Neanderthal genome sequence against the human sequencing coming out of the Human Genome Project.

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