Research has shown more women worldwide are affected by dementia than men, and a new large-scale study suggests gender-based social and economic disadvantages may be to blame.
in the Journal of the Alzheimer's Association on Feb. 15. Of the participants studied, 58 per cent were women, none had dementia at the onset of the research, and 2,089 had been diagnosed with dementia as of later followup. The period between study onset and followup ranged from 0.01 to 19.6 years, depending on the patients and the studies they participated in.
Lead author Jessica Gong, from the George Institute for Global Health, said the findings challenge previous research that suggested women face a greater risk of developing dementia than men because they live longer, on average. According to the study, the number of people living with dementia is expected to surpass 150 million worldwide by 2050 – three times the 2019 estimate of 50 million – and rates are increasing most rapidly in low- and middle-income countries.
“We found that older age, diabetes, depression, hearing impairment and having a certain genetic variation involved in fat metabolism in the brain – known as APOE4 - were associated with a greater risk of dementia in both women and men,” Gong said.
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