📹 NeilSkolnik gives a quick summary of guidance on incorporating new agents that provide alternatives to statin monotherapy.
. The randomized controlled trial of bempedoic acid with cardiovascular endpoints isn't expected to be completed until the end of 2022.
Categories 2 and 3 have similar recommendations. These are patients with an LDL cholesterol level > 190 mg/dL and people aged 40-75 years with diabetes. Start with a statin, either medium or high intensity. If the patient doesn't get to goal with the statin, then consider either ezetimibe or a PCSK9 mAb. After that, if still not at goal, then consider bempedoic acid or inclisiran.
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