Researchers say a COVID-19 nasal spray could be available to Australians within a couple of years after potential human trials in 2024.
He said there will need to be work to see if the findings hold for humans, but so far the results look promising.
Compared to the control group, the authors found a significant result: complete protection against infection and "sterilising lung immunity" had been established at the eight-week mark.What's the verdict - how effective are COVID-19 nasal sprays in humans?Professor Britton said once safety and efficacy in human populations is established, then a number of population groups would see particular benefit from the cheaper cost, convenience and less invasive method of vaccine delivery.
Another group are those with weakened immune systems who do not get the same level of immune protection from vaccines compared to the general population."That then involves problems of repeatedly immunising people . If we have a vaccine that can stimulate immunity but in a much simpler, safer and acceptable route of delivery - yes, we think that's a real advantage."
Professor Britton said the results from human trials will be crucial in unpacking the full scope of benefits in reducing transmission, but cautioned the nasal spray alone will not eliminate the virus completely.He said the goal is to reduce virus transmission levels in the community.
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