Losing a loved one linked to faster biological aging

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Losing a loved one linked to faster biological aging
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Losing someone close, like a family member, can make you age faster, says a new study from Columbia University Mailman School of Public Health and the Butler Columbia Aging Center.

Columbia University's Mailman School of Public Health Jul 29 2024 The study found that people who lost a parent, partner, sibling, or child, showed signs of older biological age compared to those who hadn't experienced such losses. The research was published in JAMA Network Open.

Allison Aiello, PhD, the James S. Jackson professor of health longevity in Epidemiology and the study's lead author To measure familial loss during childhood or adolescence from the longitudinal study, Aiello and colleagues followed participants through various waves, and aging timeframes. Wave I surveyed 20,745 adolescents in grades 7-12, most of whom were aged 12-19. Participants have been followed ever since. Wave V took place between 2016 and 2018 and completed interviews with 12,300 of the original participants.

People who experienced two or more losses had older biological ages according to several epigenetic clocks. Experiencing two or more losses in adulthood was more strongly linked to biological aging than one loss and significantly more so than no losses. Aiello and her co-authors emphasize that while loss at any age can have long-lasting health impacts, the effects might be more severe during key developmental periods like childhood or early adulthood. "We still don't fully understand how loss leads to poor health and higher mortality, but biological aging may be one mechanism as suggested in our study. Future research should focus on finding ways to reduce disproportionate losses among vulnerable groups.

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