As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.
May 15 2024University of California - Berkeley Like many athletes, he blamed it for the performance fatigue and muscle soreness he experienced after intense workouts.
The results show that the rapid conversion of glucose to lactate, starting initially in the intestines, is a way for the body to deal with a sudden dose of carbohydrates. Lactate, working with insulin, buffers the appearance of dietary glucose in the blood. They then drank 75 grams of glucose, a rapidly absorbed sugar, to stimulate a switchover from fatty acid to carbohydrate metabolism. This is similar to the glucose tolerance test used to diagnose diabetes and is commonly given to pregnant women to screen for gestational diabetes.
The researchers found that the volunteers began converting the dietary glucose into lactate before it even left the intestines. Levels of lactate began rising in arterial blood a mere five minutes after the meal, while glucose, often touted as the energy currency of the body, only showed up in the bloodstream 15 to 30 minutes after glucose ingestion.
"I think this is so revolutionary. But it's really confusing to people. What was bad now is good. All the books are wrong."
Glucose Blood Diabetes Exercise Fatigue Fatty Acids Kinesiology Laboratory Metabolism Muscle Oxygen Physiology Research
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