Covid: ongoing loss of smell may be caused by nasal cell destruction

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Covid: ongoing loss of smell may be caused by nasal cell destruction
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Research into immune response sheds light on question of whether virus damages nose or brain

Millions of people who lost their sense of smell after contracting Covid may have an ongoing, abnormal immune response that destroys cells in the nose, researchers say.

“It appears that there is an unresolved local immune response, which the delicate olfactory cells are seeing,” he added. When the researchers looked at the number of sensory nerve cells involved in smell, they found that those who suffered long-term loss of smell had notably fewer, possibly because the delicate tissue of the nasal lining had been damaged by the T-cell-driven inflammation. Similar wayward immune responses might explain other symptoms of long Covid, Goldstein said.

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