Leslie Ann Coles knew 'almost immediately' something was wrong after her COVID-19 infection in January 2021.
Leslie Ann Coles knew "almost immediately" something was wrong after her COVID-19 infection in January 2021.
Now, a team led by the Centre for Addiction and Mental Health has found physiological evidence of brain inflammation in people with cognitive and depressive symptoms months after their COVID-19 infections. "Our study shows that there's inflammation months to over a year later in people who've got long COVID."
They found that people who had long COVID had higher levels of translocator protein, or TPSO, in their brains. TSPO appears on glial cells, which increase with inflammation. Long COVID sufferers have been eagerly awaiting these findings "for validation that brain fog is real and caused by functional changes from COVID-19," said Susie Goulding, founder of the COVID Long-Haulers Canada online support group, which helped recruit study participants.
"It's been difficult to measure inflammation in patients." she said. "This study shows that in people with persistent depressive and cognitive issues, that there is neural inflammation in the brain."
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