An extremely rare case report of rebound multi-system inflammatory syndrome in children researchsquare rare disease report publichealth outbreak disease childhealth casestudy
By Neha MathurApr 12 2023Reviewed by Lily Ramsey, LLM In a new scientific paper published on the Research Square* preprint server, researchers described the case report of a five-month-old infant boy experiencing rebound multi-system inflammatory syndrome in children .
The main characteristics of MIS-C are systemic hyperinflammation, persistent fever, and multi-organ frailty, all related to severe acute respiratory syndrome coronavirus 2 infection. After four days of treatment with methylprednisolone, IVIG, ceftriaxone, and aspirin, all MIS-C symptoms except the lung sounds resolved.
Based on the American College of Rheumatology clinical guidance, the doctors gave methylprednisolone at the dosage used during the initial treatment. Findings Currently, MIS-C-related death rate is ~1.7%. Though most patients with cardiac issues recover, coronary artery aneurysms could persist in 20% of patients; however, in this case, it did not.
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