Researchers have found a link between sleep medication and the lowering of Alzheimer's-related proteins. — via healthing_ca AlzheimersRes healthing alzheimers brainhealth
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Alzheimer’s disease is the most common cause of dementia in the world, accounting for 60 to 80 per cent of all cases,. More than 747,000 Canadians are currently living with the disease or another form of dementia. Roughly 65 per cent of people diagnosed with the disease after the age of 65 are women.
Suvorexant, the sleep aid used by researchers, belongs to a class of insomnia medications known as dual orexin receptor antagonists. Orexin is a naturally produced biomolecule that helps humans stay awake; when it’s blocked, they fall asleep. Three such inhibitors have already been approved by the U.S. Food and Drug Administration, with more on the way.Lucey and his team were able to show that people who do not sleep well are more likely to have both amyloid and tau proteins in the brain.
They team found that amyloid levels dropped 10 to 20 per cent in the group who received the high dose of suvorexant compared to the placebo group. Levels of a key form of tau also fell by 10 to 15 per cent, compared to people who had received the placebo. Both these findings are statistically significant but there was no significant difference between the groups who received a loss dose and those who received a placebo.
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Alzheimer’s disease proteins reduced by sleep aidResearchers have found a link between sleep medication and the lowering of Alzheimer's-related proteins. — via healthing_ca AlzheimersRes healthing alzheimers brainhealth
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