While researchers have yet to find the proverbial fountain of youth, their discoveries have given more insight on the science behind aging.
Aging is one of the most significant risk factors for many diseases, including cancers and neurodegenerative disorders like Alzheimer’s—and the older a person is, the more likely they are to have multiple chronic illnesses.
Dr. Richard J. Hodes, director of the National Institute on Aging, said a study effectively demonstrated that when mice eat one meal per day and had the longest fasting period, they seemed to have a longer lifespan and better outcomes for common age-related liver disease and metabolic disorders. In a 2018 clinical trial funded by pharmaceutical company Novartis, 264 volunteers 65 and older received one or both of the drugs, or were assigned to a control group with placebos. Those who had taken low doses of both drugs reported 1.49 respiratory infections over one year on average, versus 2.41 in the placebo group.
Senolytics are a class of drugs that selectively eliminate senescent cells, which may help to slow the aging process. In 2016, two separate research groups published findings on the discovery of new senolytic drugs, which selectively kill senescent cells. Studies led by the University of Arkansas showed the drug ABT-263 could selectively kill senescent cells and make tissue young again.
Interestingly, incorporating resveratrol into dietary supplements or foods has become a popular option for anti-aging, and reports suggest that resveratrol treatment may have beneficial effects, including slowing bone loss.
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