Research challenges established view of the disease and its association with aging.
The teen’s memory decline started with an inability to focus in class about two years before the consultation with the clinic, the study says. As his cognitive ability deteriorated, he had trouble reading, remembering events from the day before and would misplace his belongings.
The adolescent, being unable to finish homework, could not remember whether he had eaten or even react to things fast enough, and had to drop out of high school. The results of an auditory and learning test further confirmed a memory disorder, placing him far behind his peers in short- and long-term memory recall.Article content
A sample of the young patient’s cerebrospinal fluid had a high concentration of p-tau181, while a PET scan showed mild hippocampal atrophy, the study says. Both indicators led the authors to diagnose him with “probable” Alzheimer’s disease. Strangely, though, a whole genome sequence showed no inherited gene mutations for the condition, which younger patients typically have.
The patient also has no family with a history of the disease or any head trauma or disease that could explain his diminished cognitive ability. The perplexing and rare case was recently published in theFor more health news and content around diseases, conditions, wellness, healthy living, drugs, treatments and more, head to
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